EXPIN

Our Mission

Universal access to precision medicine.

We build tools that help clinicians and patients identify the treatable environmental and lifestyle causes of chronic disease that are often overlooked in conventional, reactive care.

Genes load the gun. Exposures pull the trigger.

At EXPIN, we are focused on bringing the science of the exposome to patient care. The exposome is the lifetime accumulation of everything you've been exposed to, from chemicals and infections to medications, stress, and diet, and how it interacts with your unique biology to drive disease.

Over 70% of chronic illness is driven by these non-genetic factors, yet investigating these links has historically taken experts months of painstaking work, putting precision medicine out of reach for all but the wealthiest patients or those sick enough to qualify for clinical trials.

We aim to change that.

Our Values

  • Evidence-based — We show our work. Every claim links to primary sources.
  • Courageous — We call out influencer-fueled pseudoscience and challenge reactive care models. We don't hedge when the science is clear, and we adapt when new science emerges.
  • Compassionate — We honor the patient journey and respect clinician constraints. We build tools that empower, not burden.

Leadership & Expertise

The Exposome Intelligence Company is a privately owned, venture backed startup based in New York City, built by a multidisciplinary team of biomedical scientists, AI engineers, and clinical experts.

Krisna Bhargava, PhD — Founder & CEO

Serial entrepreneur, scientist, and inventor with nearly two decades of experience bridging complex science and impactful product design. Prior to EXPIN, Dr. Bhargava co-founded ARENA, a venture-backed robotics company acquired in 2024 and held various product leadership and engineering roles at Tabs Platform, Juno Diagnostics, Stanford Research Systems, Lockheed Martin Advanced Technology Center, and NASA Ames Research Center. Co-author of dozens of patents and peer-reviewed papers, including a PNAS cover article. PhD in Materials Science from the University of Southern California, Viterbi School of Engineering (completed in a record 3 years and named to Inc. Magazine's 30 Under 30.); postdoctoral fellowship at USC in collaboration with the Children's Hospital Los Angeles; BS Electrical Engineering from the University of California, Santa Barbara.

Jonathan Freedman, PhD — Head of Science

Internationally recognized toxicologist and one of the foremost experts on how environmental exposures drive human disease at the molecular level. 40+ years of senior academic and federal leadership, including as an NIH Investigator (NIEHS) and faculty at Duke, University of Louisville, and University of North Carolina Chapel Hill. Currently chairs key working groups for PrecisionTox, a €20M EU initiative developing AI-driven alternatives to animal testing. 100+ peer-reviewed publications and multiple patents in stress-regulated gene expression. PhD in Molecular Pharmacology from the Albert Einstein College of Medicine.

Uta Guo, MD MBA — Head of Medicine

Board-certified family physician with MemorialCare Medical Group. Previously, Assistant Professor of Family Medicine and Community Health at the Icahn School of Medicine at Mount Sinai. Her specialized research focus on clinical informatics and physician burnout was cultivated during her training and research at NewYork-Presbyterian Brooklyn Methodist Hospital where she quantified lost patient-facing time due to Electronic Health Record systems. A graduate of St. George's University with an MD and MBA, Dr. Guo has published influential work on Electronic Health Record (EHR) optimization. Dr. Guo is dedicated to using evidence-based medicine with a holistic approach to form deep, longitudinal patient-physician relationships.

Advisory Board

Leonardo Trasande, MD MPP — Environmental Health & Pediatric Epidemiology

Internationally renowned leader in quantifying how environmental exposures drive chronic disease and Jim G. Hendrick M.D. Professor of Pediatrics at NYU. He is best known for his landmark studies documenting over $340 billion in annual U.S. health costs linked to endocrine-disrupting chemicals and for authoring the book, Sicker, Fatter, Poorer. He currently leads a major cohort center for the NIH's Environmental Influences on Child Health Outcomes (ECHO) program. An advisor to the World Health Organization and the United Nations, Dr. Trasande holds medical and public policy degrees from Harvard and previously served as a legislative fellow for Senator Hillary Rodham Clinton.

Robert (Bob) Molinari, PhD MBA — Biotechnology Strategy & Platform Innovation

Veteran serial entrepreneur and strategic advisor with 35+ years launching disruptive companies in genomics, synthetic biology, and neurodegenerative disease and Principal at MedStars. Founding CEO of Retrotope (novel therapies for orphan neurological diseases) and co-founder of Protogene Laboratories (acquired by Life Technologies). More recently co-founded Repoxegen Therapeutics, developing first-in-class therapies targeting fatty-acid metabolism. Former McKinsey consultant; PhD in Biophysical Chemistry from Brown, MBA from Dartmouth. Advisor to Affymetrix, Sequenom, and other platform pioneers.

Kuljeet Rai, MD — Precision Care & Clinical Investigation

Concierge family physician (MDVIP) and clinical researcher with 30+ years at the intersection of frontline primary care and medical innovation. Former Co‑Chief Resident in Family Practice at Stanford and long‑time attending at Good Samaritan Hospital in San Jose. Adjunct Assistant Professor of Medicine at Stanford and USC since 1993, with leadership in clinical trials including the Jupiter Trial for coronary artery disease prevention. Department Chair of Family Practice at San Jose Medical Group/Good Samaritan Medical Group; known for a highly personalized "quarterback" style of care for complex, chronically ill patients.

Quinto Gesiotto, MD MS — Molecular Hematology & Hematologic Malignancies

Dr. Gesiotto is a hematologist and medical oncologist at the Tampa General Hospital Cancer Institute, where he specializes in the treatment of leukemia and myeloid malignancies through high-resolution molecular diagnostics. He served as the Chief Hematology Fellow at Thomas Jefferson University's Sidney Kimmel Cancer Center and completed his clinical training and residency at the University of South Florida. He was a member of the inaugural MD class at California Northstate University and received an MS Medical Science from Boston University.

Reach Out to Our Team